12 August

VFS - instructions for use , testimonials, testimony

VFS - a drug for the treatment of diseases of the cardiovascular system.

release form and composition

Allapinin produced in the form of tablets and solution.

The structure of the round, biconvex white tablets includes:

  • lappaconitine hydrobromide (VFS) - 25 mg;
  • Sucrose (sugar, refined sugar or granulated sugar) - 65.5 mg;
  • Potato starch - 7.5 mg;
  • Calcium stearate (calcium stearate) - 1 mg;
  • Croscarmellose Sodium - 1 mg.

Solution for intravenous or intramuscular injection contains 2 ml of 5 mg / ml of active ingredient.

Indications

According to the instructions, VFS is used for heart rhythm disturbances:

  • Ventricular and supraventricular arrhythmia;
  • paroxysms of atrial flutter and atrial fibrillation;
  • Ventricular and supraventricular paroxysmal tachycardia.

Contraindications

Applications VFS is contraindicated in:

  • cardiogenic shock;
  • severe hypotension;
  • renal or hepatic impairment;
  • Siege intraventricular conduction;
  • Chronic heart failure II-III degree;
  • blockade of the right bundle branch block;
  • Pregnancy;
  • Lactation.

under medical supervision taking the drug, children and adolescents up to 18 years, and patients with:

  • compensate for chronic heart failure;
  • bradycardia;
  • angle-closure glaucoma;
  • prostatic hypertrophy;
  • blockade AV I degree;
  • conduction abnormalities on Purkinje fibers;
  • electrolyte imbalance;
  • blockade of one of the branch block feet;
  • cardiomegaly.

Caution is required when pacing.

During treatment it is necessary to take into account that the use of VFS enhances the action of non-depolarizing muscle relaxants.

Efficiency Allapinin reduce inducers of microsomal liver enzymes, anti-arrhythmic agents of other classes.The combination with inhibitors of microsomal oxidation can cause toxic complications.

Dosage and Administration

Allapinin by instructions taken every 8 hours to 0,025 g

If there is no effect, the daily dose can be increased by increasing the multiplicity of reception - every 6 hours.Acceptable unit dosage increase up to 0.05 g, are administered every 6-8 hours.

course of treatment may last for several months.In general, the duration depends on the degree of cardiac arrhythmias, and general condition of the patient.

maximum allowable dose: daily - 0,3 g, single - 0.05 g

action of the drug with an internal application starts after 40-60 minutes after taking the tablets and lasts for more than 8 hours.

For intramuscular and intravenous use Allapinin dilute sodium chloride solution and administered intramuscularly every 6 hours a dosage of 0.4 mg / kg and intravenously - 0.3-0.4 mg / kg for 5 minutes.

After 6 hours, if necessary, you can enter a second dose - 0.3 mg / kg.

Intravenously, the therapeutic effect begins after 15-20 minutes and persists for 6-8 hours.

Side effects

VFS can cause headache, ataxia, dizziness, diplopia, sinus tachycardia, slowing intraventricular conduction, reddening of the skin reactions of allergic nature.

Cautions

When side effects should reduce the dose.

Analogues Analogues

Allapinin by active ingredient no.A related mechanism of action has Etmozin.

Terms and conditions of storage

Store at temperatures not above 25 ° C.Keep away from children.Shelf life - 5 years.

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