Hydrocortisone - a hormone drug steroid nature, which is produced by the adrenal cortex and is involved in carbohydrate and protein metabolism.
Pharmacological group - steroids.
The drug is available in the following forms:
drug Hydrocortisone - a synthetic glucocorticosteroid agent for systemic and local use, with a strong high-speed anti-inflammatory, antiexudativ (decongestant), antisense (anti-allergic) immunosuppressive, antishock and antitoxic action.
Hydrocortisone through a certain chain reactions inhibits the release of inflammatory mediators.The immunosuppressive effect of the drug due to inhibition of the reactions of the immune system.
For topical use Hydrocortisone
For topical use eye drops and eye ointment Hydrocortisone in inflammatory processes in the anterior chamber of the eye without damaging the cornea:
periarticular or intraarticular (Hydrocortisone Acetate in suspension):
intradermal injection (hydrocortisone acetate in suspension):
Systemic therapy (inside, in / m / w) hydrocortisone suspension, tablet, powder for injection:
For external and topical use Hydrocortisone:
wary recognize cases: pregnancy (I trimester) and lactation, systemic failure in tuberculosis, diabetes.
If systemic therapy hydrocortisone require caution:
According to the instructions for the application of hydrocortisone Hydrocortisone possible occurrence of some undesirable side effects.
When applied topically, can develop allergies, burning, inektsirovanie vessels sclera;In the case of prolonged use Gidrokorizona drops or eye ointment Gidrokorizon may develop subcapsular cataracts, glaucoma and exophthalmos;
For external use can occur allergic skin reactions.
Local and general systemic side effects occur in the case of prolonged use of Hydrocortisone on very large surfaces or in areas of damaged skin, as well as when using Hydrocortisone Ointment under occlusive dressings.
When using hydrocortisone for systemic therapy, the following side effects:
part of the endocrine system:
From the musculoskeletal system:
part of the intestine:
part of the skin and mucous membranes:
CNS and organs of vision:
Other side effects: immunosuppressive conditions, violation of water-electrolyte metabolism, increased blood pressure, vasculitis.
When emergencies recommend the use of hydrocortisone intravenously.
adult dose starts from 100 ml to 450-500 ml and more, depending on the severity of the patient's condition.Assign to 1500 mg / day.
/ m adults - 125-200mg per day
children - 15-30 mg per day, dividing the dose into several times.
intra-articular and periarticular Hydrocortisone administered in suspension:
Hydrocortisone Ophthalmic Ointment is introduced into the conjunctival sac of 1, 2 or 3 times a day.
Hydrocortisone Ointment is applied in a thin layer on the skin no more than four times a day, a course of treatment is not more than three weeks.
According to the instructions of hydrocortisone, the initial dose for oral administration is 20-240ml, followed ёё decline.However, with exacerbation of multiple sclerosis, the dose may be increased to 800mg per day., Followed by reduction.
Store at room temperature.
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