12 August

Calcium Hydroxyapatite - instruction , used in cosmetology

Sa10 calcium hydroxyapatite (PO4) 6 (OH) 2 is an inorganic main component of bone.

Produce Hydroxyapatite drug coral genus Porites, which is mined in the sea.Absolutely inert to human tissues due to this has been widely used in dentistry, traumatology, maxillofacial surgery.In cosmetology Hydroxyapatite is used to smooth out wrinkles.

Pharmacological group: control Calcium-phosphorus metabolism


calcium hydroxyapatite produced in the form of a powder, suspension, granules and pastes.

Pharmacological action

adjusting the exchange of calcium and phosphorus, the tool itself is the base matrix of bone tissue is inorganic nature.By activating bone formation, increased proliferation of osteoblasts and injection site started the process of reparative osteogenesis, which inhibits inflammation in the bone wound.Once the cavity is filled with bone, calcium hydroxyapatite does not harden and does not resolve, as is its full replacement bone tissue.

Gidroksipatit calcium low toxicit

y, if its application is not observed side effects (inflammation, allergy, mutagenic effect).

Indications Hydroxyapatite

for stimulation of reparative osteogenesis in maxillofacial and plastic surgery, traumatology and dentistry Hydroxyapatite used:

  • as the fulfillment of the missing elements of bone tissue;
  • periodontitis;
  • to restore bone defects after removal of seizures;
  • in wounds with damage to bone (eg gunshot.);
  • in different types of fractures;
  • formed with false joints;
  • for the introduction of stents and implants;
  • with plastic facial bones.

for use as a filler ingredient in dental filling pastes used in Hydroxyapatite:

  • pulpitis;
  • periodontitis;
  • replenishment of bone defects - after removal of cysts;
  • fill defects after resection (partial removal) apex;
  • deep caries;
  • to fill root canals.

Hydroxyapatite is also used in cosmetics for intradermal injections for wrinkles.


In the case of individual hypersensitivity to the drug.

Side effects

not observed.

Instructions for use Hydroxyapatite

calcium hydroxyapatite powder is mixed with saline and etilglikolem either oily solution retinolatsetata to pasty consistency.The paste must be used within two minutes after its preparation.

calcium hydroxyapatite in granules are used to fill the pockets with periodontitis.To do this, prepare a pocket in advance, and then densely fill his beads

Hydroxyapatite as a finished paste can be directly introduced into the injured, previously prepared piece of bone (remove the changes, or necrotic tissue) or the place where you want to fill the defect, followed by stratified stitching soft tissue.

5% suspension was injected into the cavity of bone defect with a syringe.

To restore the previous height mezhalveolyarnyh partitions and filling defects of the alveolar bone using 45% paste.

for periodontal therapy using 18% hydroxyapatite paste.

10% suspension of hydroxyapatite used in the case of conservative treatment of periodontitis.

for wrinkles in cosmetic Hydroxyapatite administered by intradermal injection as a filler in the form of an aqueous solution.


use of the drug for the restoration of bone tissue in the acute phase of inflammation of soft tissues accompanied by suppuration is considered inappropriate.If necessary

Hydroxyapatite can be sterilized in a hot air oven with an infinite multiplicity of repetitions at temperatures up to 150 C, at least 10-15 minutes at exposition.


Store in a dry place.

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