Macropen - macrolide antibiotic, has bactericidal effect, in the low to high doses - bacteriostatic.
active substance macrofoams:
shell consisting of tablets: macrogol, methacrylic acid copolymer, titanium dioxide, talc.
wary Macropen recommended to prescribe to patients with an indication of a history of hypersensitivity to acetylsalicylic acid.
During pregnancy, use of the drug is shown in an emergency, provided that the expected clinical benefit to the mother is much higher than the potential risk to the fetus.
The use of tablets is contraindicated under the age of 3 years.
tablets and granules prepared from the suspension is taken orally before a meal.
slurry is prepared by dissolving the contents of a vial of 100 ml with distilled or boiled water.The suspension is suitable for use within 7 days of storage at room temperature and 14 days - when stored in the refrigerator.Before each reception suspension should be well shaken.
dose and the period of application assigns physician based on clinical indications.
Recommended dosage for tablets:
daily dose for children is assigned a suspension rate of 50 mg per 1 kg of body weight of the child and taken in 2 hours using the measuring spoon.
single dose suspension has weight restrictions:
course of treatment is 7-14 days for chlamydial infections - 14 days.The daily dose
macrofoams diphtheria determined by the rate of 50 mg per 1 kg weight of the patient and is taken in 2 hours.The duration of treatment 7 days, then it is recommended to control bacteriological examination.
Prevention of pertussis is performed during the first 14 days after contact with an infected at a dose of 50 mg per 1 kg of body weight per day, course of treatment - 7-14 days.
macrofoams Application for a long time can lead to excessive growth of resistant bacteria and the development of pseudomembranous colitis, which is a strong sign of prolonged diarrhea.
Long-term therapy requires regular monitoring of liver enzymes, especially in patients with liver function disorders.
Mannitol, a part of the granules may cause diarrhea.
patients with hypersensitivity to acetylsalicylic acid should be aware of a history of the cause of allergic reactions, including bronchospasm, may be colorant sunset yellow (E110) as a part of the granules.
The drug does not affect the patient's ability to drive vehicles and mechanisms.
Use caution when combined with the drug carbamazepine and ergot alkaloids, since the action macrofoams reduces their rate of metabolism in the liver and increase the level of concentration in the blood serum.
Simultaneous treatment with cyclosporine, warfarin, and other anticoagulants slows their rate of excretion.
drug does not infringe the pharmacokinetics of theophylline.
Keep away from children.
Store at temperatures up to 25 ° C, pills - in a dry place.
Shelf life - 3 years.
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