12 August

Rimantadine - instructions for use , testimonials, testimony

Remantadinum

composition and the form of release

The composition of one tablet of 50 mg includes rimantadine.The drug comes in tablet form.

pharmacological action of rimantadine

From rimantadine instruction that is an antiviral agent, a derivative medantana and amantadine.It is used as an anti-Parkinsonian drug agent.Rimantadine simultaneously with the chemotherapeutic agent is an antiviral activity.Rimantadine is actively fighting the influenza viruses A virus encephalitis.The drug has immunomodulatory and anti-toxic effect.

rimantadine Prolonged circulation in the body to ensure its polymer structure.Thus, the long half-life of the drug is to assign Remantadin not only for therapeutic purposes, but also for the prevention of influenza and encephalitis.

As a result of rimantadine was found that the drug inhibits the reproduction of a particular virus early on, promotes the production of interferons alpha and gamma, increases the functionality of the lymphocytes.Rimantadine prevents lea

ving viral particles from the cells, disrupting the transcription of the viral genome.

Many patients give positive feedback about the rimantadine, taking medication as prophylaxis.The drug reduces the risk of getting the flu, and in the presence of the disease contributes to a speedy recovery.Particularly active therapeutic effect of rimantadine will occur when using the drug in the first 18 hours of poor health are the initial stages of the disease indication for rimantadine.

Pharmacokinetics

Rimantadine is absorbed in the digestive tract after 2-4 hours after ingestion.The degree of plasma protein due to about 40%.Actives rimantadine metabolized in the liver.The half-life of the drug from the body is approximately 25-30 hours.In elderly patients and patients with impaired renal function, and hepatic elimination half-life is increased.In children, the half-life decreases rimantadine.

Indications rimantadine

rimantadine are indications for prevention and treatment at an early stage of influenza in children over 7 years and adults, prevention of tick-borne encephalitis.

Dosage

Remantadin taken orally after a meal.The maximum therapeutic effect is reached if to begin treatment immediately after onset of symptoms.Duration of treatment and dosage should be determined by a specialist.

As a rule, the first day of adolescents and adults are advised to take 300 mg of rimantadine.The daily dose is divided into several stages.In the second and third day of disease taking 100 mg twice a day.In the fourth and fifth day - 100 mg rimantadine once daily.

In rimantadine instructions indicate that for children aged 11-14 years, the daily dose should not exceed 150 mg for children aged 7-11 years should take 100 mg a day rimantadine.The duration of treatment of influenza - 5 days.

As a preventive measure prescribe 50 mg per day rimantadine.The duration of prophylaxis for 10-15 days.

People participating in the campaigns on forest areas as prevention of tick-borne encephalitis is recommended to take Rimantadine 2 times daily 50 mg.prevention course of 15 days.

Side effects rimantadine

Most often, experts receive positive feedback about the rimantadine.But sometimes medication can have adverse effects on the central nervous system: headaches, poor concentration and memory, dizziness.

may experience stomach pain, vomiting, loss of appetite.

allergic reaction to Rimantadine are itching and hives.In epilepsy patients the risk of seizures is increased.When using rimantadine chronic diseases may worsen.

Not recommended simultaneous with caffeine product as well as the effect of the drug is enhanced on the central nervous system.

When you receive increased doses of rimantadine is necessary to gastric lavage.In the case of overstimulation, hallucinations, cardiac arrhythmia is an urgent need to consult a doctor.

Contraindications

In rimantadine instructions are not allowed the drug to patients with active liver disease, chronic and acute renal disease, with increased sensitivity to the drug, thyrotoxicosis, pregnancy and lactation.Children under 7 years is a contraindication for use rimantadine.

interaction with other drugs rimantadine

the treatment with this drug decreases the effectiveness of anti-epileptic agents.Enveloping, astringents, absorbents reduce the absorption of rimantadine.

Ascorbic acid and ammonium chloride reduces the effectiveness of the drug.

Sodium bicarbonate and atsetozalamid enhance the effectiveness of rimantadine.

Additionally

If a patient during treatment with antiepileptic drugs takes, it is necessary to reduce the dose of rimantadine to 100 mg per day.With careful preparation is assigned to the elderly.

the treatment rimantadine can cause disorders of the nervous system, so it is advisable to use caution when driving and when working with dangerous machinery.

storage and release conditions

drug should be stored in a dry place away from children at a temperature of 25 degrees Celsius.Sold without prescription.Shelf life 5 years.

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