12 August

Spazgan - instructions for use , indications , composition, reviews

spazgan is a combined preparation belonging to the group of antispasmodic and analgesic agents.The drug comes in tablet form and a solution for intravenous injection.

Tablets: flat, round white or yellowish color with the logo on one side and scored on the other.

Injection: colorless, transparent or slightly yellowish tinge.

spazgan Composition:

1 drug tablet contains 500 mg of sodium metamizol, 5 mg pitofenone hydrochloride and 100 mg fenpiveriniya bromide.

1 vial of solution for injection contains 1 g of sodium metamizol, 400 mcg pitofenone hydrochloride and 4 mg fenpiveriniya bromide.

spazgan Three-structure leads to a strengthening of their pharmacological action.

Pharmacological action spazgan

The instructions to Spazganu noted mutual reinforcement properties of the drug due to the combined combination of components that have analgesic and antispasmodic properties.Metamizole has antipyretic and analgesic effects, and are part of spazgan pitofenone hydrochloride and fenpiveriniya bromide r

elaxes smooth muscles, rendering it complex papaverinopodobnoe action.


spazgan Application is recommended for mild to moderate pain syndrome, spasms of the smooth muscles of the intestine, bladder and ureter, renal, gastric, biliary colic.Reviews Spazganu to confirm the efficacy of the drug with biliary dyskinesia, chronic colitis, postcholecystectomy syndrome, diseases of the pelvic organs.In some cases, a drug used in therapeutic treatment of intermittent myalgia, arthralgia, neuralgia, sciatica.

also indications Spazganu not exclude the use of the drug as an aid in removing pain after diagnostic procedures and surgical interventions.


drug is not recommended for use in the presence of hypersensitivity to the components forming part of spazgan (including pyrazolone derivative), renal and liver failure, severe angina, tachyarrhythmias, prostatic hyperplasia, intestinal obstruction.Do not use spazgan during pregnancy (especially in I and III trimester), breastfeeding.During pregnancy, the drug is justified only if the indications Spazganu higher than the risk of the fetus malformations.

When administered intravenously spazgan contraindicated in infancy (up to 3 months), tablets - in children under 5 years old.

Side effects

According to Spazganu instructions, the drug has the following side effects:

  • From the urinary system: oliguria, renal dysfunction, proteinuria, anuria, urine staining in red color;
  • the part of the cardiovascular system and the blood: decreased blood pressure, tachycardia, heart rhythm disturbances, thrombocytopenia, agranulocytosis, leukopenia;
  • the part of the central nervous system: headache, dizziness.

The feedback to Spazganu marked the possible allergic reactions: angioedema, urticaria, in rare cases, - Stevens-Johnson syndrome (malignant exudative erythema), bronchospastic syndrome, epidermal necrolysis, anaphylaxis.

In overdose symptoms of hypotension may occur, vomiting, drowsiness, nausea, convulsions, kidney and liver function.As treatment apply gastric lavage, activated charcoal, other symptomatic therapy.

interaction with other drugs

Despite the indications Spazganu, solution for injection is not recommended to combine with other drugs.In a joint application with butyrophenones, tricyclic antidepressants, phenothiazines, quinidine and amantadine, on responses to the Spazganu, increased m-anticholinergic action is observed.Simultaneous treatment with the drug chlorpromazine can cause severe hyperthermia and allopurinol and oral contraceptives increase the toxicity of the drug.According to the instructions, spazgan not compatible with penicillin, colloidal blood substitutes and radiopaque drugs.


The application period spazgan not recommended to take ethanol, alcoholic beverages, drive and engage in activities that require the speed of mental and physical reactions.

The feedback to Spazganu warned about the need to control the treatment of the content of leukocytes in peripheral blood.At the slightest suspicion of thrombocytopenia and agranulocytosis, it is recommended immediately stop taking the drug!Spazganom unacceptable treatment in order to reduce the acute pain in the abdomen - to determine their causes.

Application and dosage

The instructions to Spazganu states that the dosage of the drug depends on the age and characteristics of the patient's disease.Nevertheless, the recommended dosage when indicated to Spazganu is 6 tablets per day (for adults and children over 15 years old), 3 tablets per day (for children between the ages of 13-15 years old) and one tablet per day for children aged 6-12 years.Spazgan daily dose should not exceed 6 ml or 10 tablets.

Intravenous injection of the drug needs to be done slowly, under the strict control of heart rate, respiration and blood pressure.When this injection must be at room temperature.

Tablets spazgan, reviews, use inside after eating, drinking plenty of water.

Instruction Spazganu is not a recommendation to use the drug.Before use, check with your doctor!

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