L-lysine aescinat - angioprotective drug with venous and moderate hypoglycemic action.
Formulation - concentrate for solution for intravenous (i / v) administration (5 ml ampoules in blisters 5 pieces, in a cardboard bundle two packaging.).Active substance
- L-lysine aescinat in 1 ml of concentrate - 1 mg.
L-lysine aescinat intended only for the on / in the slow drip or bolus.It is strictly forbidden intraarterial!
recommended daily dose - 5.10 ml.
Do not use the drug without prior dilution.
solution for the on / in
should be increased to 20 ml in traumatic brain injury, post-operative swelling of the spinal cord and brain with symptoms of edema, swelling, extensive soft tissue swelling due to injury and other life-threatening conditions of the patient and the daily dose is administered in equally in 2 divided doses.The course of the drug depends on clinical indications and effectiveness of treatment and may last from 2 to 8 days.
Against the background of individual intolerance of L-lysine aescinat may develop undesirable effects:
Appointment drug to patients with hepatocholecystitis in some cases may cause a transient increase in bilirubin and transaminases, which is not a threat and does not require discontinuation of therapy.
The composition concentrate includes ethanol in the amount of 23.8% or up to 2.4 ml in single and up to a daily dose of 6.1 ml.
Precautions should be prescribed the drug for epilepsy, alcoholism, liver disease.
The use of L-lysine aescinat may affect the patient's ability to drive vehicles and mechanisms.
while the use of L-lysine aescinat can improve their nephrotoxicity.
At long previous treatment with anticoagulants or necessity of their combination with the drug dose should be adjusted under control of anticoagulants prothrombin index.
Concomitant antibiotic cephalosporin therapy hinders the binding of L-lysine aescinat to plasma proteins and increases the risk of its side effects, with increased concentration of free escin in the blood.
should take into account the presence of 96% ethanol in the composition of the drug, while the appointment of other drugs.
Store in a dark place at a temperature of 15-25 ° C.Keep away from children.
Shelf life - 2 years.
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