L-thyroxine - thyroid medication, thyroid hormone.
drug produced in the form of tablets (10 pieces in blisters, 2, 3, 4, 5, 6, 8 or 10 packs per carton box;.. 20 or 50 pieces inpolymeric containers 1 container in a cardboard bundle; 50 pcs. in blisters, 1, 2, 4, 5, 6, 8 or 10 packs in a carton box, 50 pcs. in blisters, 1 blister cartonpack).
1 tablet contains active substance: levothyroxine sodium - 50 or 100 micrograms.
Relative (drug must be taken with caution):
overdose of L-thyroxine is shown symptoms typical for hyperthyroidism: cardiac arrhythmias, palpitations, heart pain, tremor, anxiety, sleep disturbances, increased appetite, rash, diarrhea, weight loss.The doctor may recommend (depending on symptoms): decrease the daily dose, a few days break in treatment, the appointment of β-blockers.Therapy should proceed with caution after the passage of side effects with lower doses.
tablets taken orally in the morning on an empty stomach, at least 1/2 hour before a meal without chewing and drinking a small amount (1/2 cup) of water.
daily dose of L-thyroxine is determined by the physician individually and depends on the evidence.
replacement therapy for hypothyroidism patients younger than 55 years, in the absence of cardiovascular disease, the recommended daily dose of L-thyroxine - 1.6-1.8 mg / kg body weight.Patients over 55 years, or in the presence of cardiovascular disease is determined by calculating the dose of 0.9 mg / kg body weight.Patients with severe obesity (BMI - body mass index ≥ 30 kg / m2), the calculation is made on the "ideal weight".
Initially replacement therapy in hypothyroidism the recommended dose of levothyroxine:
In the case of the emergence or worsening of symptoms of the cardiovascular system should be carried out correction treatment of cardiovascular diseases.
recommended daily dose of L-thyroxine therapy for congenital hypothyroidism, depending on the age of the child (levothyroxine dose / dose of levothyroxine per body weight):
recommended daily dose of L-thyroxine, depending on the condition / disease:
children from birth to 3 years a daily dose of levothyroxine given 1/2 hour before the first feeding (at once).Immediately prior to use the tablet must be dissolved in water to form a thin slurry.
In the case of hypothyroidism, L-thyroxine take usually lifelong.For the treatment of hyperthyroidism drug used in combination with antithyroid drugs after reaching a euthyroid state.The duration of therapy with levothyroxine in all conditions / diseases is determined by the attending physician.
In the application of L-thyroxine in compliance with all the recommendations and under medical supervision no side effects were noted.
In the case of hypersensitivity to levothyroxine possible allergic reactions.Other side-effects can only be developed with an overdose of the drug.
In the case of hypothyroidism caused by pituitary lesion, diagnosis should be carried out to find out whether both adrenal insufficiency.If a positive result to start replacement therapy corticosteroids (corticosteroids) is necessary to receive thyroid hormone for the treatment of hypothyroidism, in order to avoid the development of acute adrenal insufficiency.
Periodically monitor the TSH concentration in the blood, increase in this index indicates insufficient dose of L-thyroxine.
Levothyroxine does not affect the concentration of attention and quickness of psychomotor reactions, needed to manage the complex mechanisms and vehicles.
Mutual influence of the following substances / drugs and levothyroxine, while the application:
Store in a dry, dark, place inaccessible to children at temperature not exceeding 25 ° C.
Shelf life - 3 years.
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